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Heart failure with preserved ejection fraction is increasing in prevalence and is associated with a high symptom burden and functional impairment, especially in persons with obesity Novo nordisk) has shown benefits to prevent heart attacks and other major adverse cardiac event (mace) for those with overweight and cardiovascular disease (cvd), but the benefits of the drug on heart failure (hf) have been unknown The findings from the select trial offer crucial insights into the cardiovascular benefits of semaglutide in patients with obesity and prevalent heart failure.1 however, upon examining the discussion, specific interpretations warrant closer scrutiny

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First, while the study reports improvements in major adverse cardiovascular events and composite heart failure outcomes in patients with and. All of this held true regardless of what type of heart failure the patient had. Can wegovy or ozempic (semaglutide) be used for heart failure

Heart failure occurs when the heart can’t pump blood efficiently, leading to symptoms like shortness of breath, fatigue, and leg swelling

Treatment typically involves medications, lifestyle changes, and sometimes surgery to enhance heart function and improve quality of life. In patients with heart failure with preserved ejection fraction and obesity, treatment with semaglutide (2.4 mg) led to larger reductions in symptoms and physical limitations, greater improvements in exercise function, and greater weight loss than placebo. The authors then compared kansas city cardiomyopathy questionnaire answers from before and after those 52 weeks Overall, treatment with semaglutide was consistently associated with weight loss and improved heart failure symptoms in these patients—and the benefits seemed to actually increase for patients who were the most frail.

People with type 2 diabetes (t2d) and chronic kidney disease (ckd) are at high risk for heart failure (hf) and premature death from cardiovascular (cv) causes In addition, heart failure patients taking wegovy had a 24% reduction in deaths linked to heart disease and a 19% reduction in deaths from any cause, the study found