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As a component of proteoglycans (pgs) it has numerous roles in matrix stabilization and cellular regulation Since the functions of bgn are mediated by its chondroitin/dermatan sulfate (cs/ds) chains through the sulfates, the determination of cs/ds structure and sulfation pattern is of major. Cs has specific cell regulatory roles that control tissue function and homeostasis.

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Cs has specific cell regulatory roles that control tissue function and homeostasis Cs and ds chains are usually attached to core proteins and are present in the form of proteoglycans (pgs). Chondroitin sulfate (cs) and dermatan sulfate (ds) have been implicated in the processes of neural development in the brain

In this study, we characterized developmentally regulated brain cs/ds chains using a single chain antibody, gd3g7, produced by the phage display technique.

Chondroitin sulfate (cs) and dermatan sulfate (ds) are linear anionic polysaccharides that are widely present on the cell surface and in the cell matrix and connective tissue