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Abstract biologics manufacturing technology has made great progress in the last decade Reduced downtime needed for cleaning, sterilization, and maintenance This applies in particular to their use in the manufacture of biopharmaceutical products based on mammalian cell cultures, such as antibodies for the therapy of cancer and autoimmune diseases

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Initially adopted for simpler processes, sut has expanded to complex bioprocessing operations, driven by the growing demand for biologics, vaccines, and personalized medicines. They provide flexibility to quickly scale out, scale up, or scale down to accommodate rapid changes in production volume requirements