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It is now believed that roth spots are the result of retinal capillary rupture and intraretinal hemorrhage See what they look like and learn what causes them. A common thread found in the conditions associated with roth spots (table 1) is a predisposition for endothelial dysfunction allowing for retinal capillary disruption.

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The darker patch is from blood that leaked out of a nearby blood vessel Roth spots are signs of bleeding that might show up during an eye exam The pale pinpoint dot at the center was the exact site of the retinal bleeding (retinal hemorrhage)

It’s white or pale because your body’s natural clotting (hemostasis) process plugged the bleeding and started repairs.

Roth spots are most commonly associated with infective endocarditis and have been detected in 80 percent of cases of subacute bacterial endocarditis. The spots are believed to result from septic emboli, which cause hemorrhages in the retina The presence of roth spots in individuals suspected of having endocarditis can aid in early diagnosis and treatment, potentially averting severe cardiac complications. Roth spots occur in a variety of diseases or conditions where there is retinal blood vessel injury

They result from a rupture of the small capillaries in the retina (a layer of cells in the back of the eye that senses light). However, new studies suggest that roth spots actually come from a broken blood vessel in the retina, causing a bleed inside the retina These roth spots can show up in many different diseases where the blood vessels in the retina are damaged, causing bleeding.