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GSK-3β的生物学特性：GSK-3最早在兔 骨骼肌 的分次提取物中被分离出来，主要有两种亚型，即GSK-3α和GSK-3β，二者在催化区域具有98%的 同源性，于N-和C-末端略有不同. Here we summarize the structure and physiological functions of gsk3β and explore its involvement in ndds. 糖原合成酶激酶-3 (GSK-3)是一种在进化上非常保守的丝氨酸/苏氨酸激酶，能作用于众多信号蛋白、结构蛋白和转录因子，调节细胞的分化、增殖、存活和凋亡。

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Gsk3 refers to two paralogs that are commonly referred to as isoforms, gsk3α and gsk3β However, gsk3β is highly expressed in different areas of the brain and has been implicated in alzheimer's … A theoretical analysis found that gsk3β has more predicted substrates than any other kinase (linding et al., 2007).

糖原合酶激酶3 (GSK-3)是一个高度保守的蛋白激酶家族。 在人类中，两个基因编码两种不同但密切相关的GSK-3形式，称为 GSK-3α 和 GSK-3β。

Glycogen synthase kinase 3 (gsk3) is one of the serine/threonine protein kinases, which has gained a lot of attention for its role in a variety of pathways It has two isoforms, gsk3α and gsk3β